Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeastSchizosaccharomyces pombe
| | 2017-04-28 16:23
Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeastSchizosaccharomyces pombe
Abstract：
A central step in the initiation of chromosomal DNA replication in eukaryotes is the asse...
CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development
| | 2017-04-28 16:16
CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical developmen
Abstract：
Studying the early function of essential genes is an important and challenging problem i...
Nonsense-mediated mRNA decay inTetrahymena is EJC independent and requires a protozoa-specific nuclease
| | 2017-04-28 16:11
Nonsense-mediated mRNA decay inTetrahymena is EJC independent and requires a protozoa-specific nuclease
doi:10.1093/nar/gkx256
Abstract：
Nonsense-mediated mRNA decay (NMD) is essential for removing premature termination codon-contain...
A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinoGENEsis
| | 2017-04-28 16:04
A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinoGENEsis
Mengmeng Ge,Junjie Hu,Xiaolei Li,Li Che,Kun Sun,Lili Cheng,Yuedong Huang,Maria G. Pilo,Antonio Cigliano,Giovanni M. Pes,Rosa M. Pascale,Stefania Brozzet...
A recombinant H7N9 influenza vaccine with the H7 hemagglutinin transmembrane domain replaced by the H3 domain induces increased cross-reactive antibodies and improved interclade protection in mice
| | 2017-04-28 15:58
A recombinant H7N9 influenza vaccine with the H7 hemagglutinin transmembrane domain replaced by the H3 domain induces increased cross-reactive antibodies and improved interclade protection in mice
Yang Wanga, Jialing Wua, Chunyi Xuea, Zhihu...
Smurf1 inhibits integrin activation by controlling Kindlin-2 ubIQuitination and degradation
| | 2017-04-28 15:50
Smurf1 inhibits integrin activation by controlling Kindlin-2 ubIQuitination and degradation
Xiaofan Wei, Xiang Wang, Jun Zhan, Yuhan Chen, Weigang Fang, Lingqiang Zhang, View ORCID ProfileHongquan Zhang
DOI: 10.1083/jcb.201609073 | P...
NOTCH1 signaling regulates self-renewal and platinum chemoresistance of cancer stem-like cells in human non-small cell lung cancer
| | 2017-04-28 15:41
NOTCH1 signaling regulates self-renewal and platinum chemoresistance of cancer stem-like cells in human non-small cell lung cancer
Yun Zhang, Wei Xu, Huiqin Guo, Yanmei Zhang, Yuexi He, Sau Har Lee, Xin Song, Xiaoyan Li, Yongqing Guo, Yu...
Posttranslational Regulation of Smads
医学研究进展 | | 2016-12-20 17:13
Posttranslational Regulation of Smads
Pinglong Xu1, Xia Lin2 and Xin-Hua Feng1,2,3
Abstract
Transforming growth factor β (TGF-β) family signaling dictates highly complex programs of gene expression responses, which are extensively regul...
HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem Cells through activating PI3K/AKT signal pathway
医学研究进展 | | 2016-12-20 17:09
HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem Cells through activating PI3K/AKT signal pathway
Mingyue Zhu,Wei Li,Yan Lu,Xu Dong,Bo Lin,Chen Yi,Xueer Zhang,Junli Guo,Mengsen Li
Accepted manuscript onlin...
Mitochondrial Control of Apoptosis through Modulation of Cardiolipin Oxidation in HepatoCellular Carcinoma: A Novel Link between Oxidative Stress and Cancer
医学研究进展 | | 2016-12-20 17:02
Mitochondrial Control of Apoptosis through Modulation of Cardiolipin Oxidation in HepatoCellular Carcinoma: A Novel Link between Oxidative Stress and Cancer
Abstract
Altered redox status in cancer cells has been linked to lipid peroxidati...
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