Cilia loss sensitizes Cells to transformation by activating the mevalonate pathway
医学研究进展 | | 2018-03-01 12:43
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway
Yue-Zhen Deng, Zhen Cai, Shuo Shi, Hao Jiang, Yu-Rong Shang, Ning Ma, Jing-Jing Wang, Dong-Xian Guan, Tian-Wei Chen, Ye-Fei Rong, Zhen-Yu Qian, Er-Bin Zhang...
Valnoctamide inhibits cytomegalovirus infection in developing brain and attenuates neurobehavioral dysfunctions and brain abnormalities
医学研究进展 | | 2018-03-01 12:37
Valnoctamide inhibits cytomegalovirus infection in developing brain and attenuates neurobehavioral dysfunctions and brain abnormalities
Sara Ornaghi, Lawrence S. Hsieh, Angélique Bordey, Patrizia Vergani, Michael J. Paidas and Anthony N....
Poor caregiver mental health predicts mortality of patients with neurodeGENErative disease
医学研究进展 | | 2018-03-01 12:30
Poor caregiver mental health predicts mortality of patients with neurodeGENErative disease
Sandy J. Lwi, Brett Q. Ford, James J. Casey, Bruce L. Miller and Robert W. Levenson
PNAS 2017; published ahead of print June 27, 2017, http...
Ribosomal DNA copy number loss and sequence variation in cancer
医学研究进展 | | 2018-03-01 11:09
Ribosomal DNA copy number loss and sequence variation in cancer
Baoshan Xu, Hua Li, John M. Perry, Vijay Pratap Singh, Jay Unruh, Zulin Yu, Musinu Zakari, William McDowell, Linheng Li, Jennifer L. Gerton
Published: June 22, 2017https:...
The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite
医学研究进展 | | 2018-03-01 11:03
The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite
Mihir Vohra, George A. Lemieux, Lin Lin, Kaveh Ashrafi
Published: August 1, 20...
Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells
医学研究进展 | | 2018-03-01 10:55
Transient Scute activation via a self-stimulatory loop directs enteroendocrine cell pair specification from self-renewing intestinal stem cells
Jun Chen, Na Xu, Chenhui Wang, Pin Huang, Huanwei Huang, Zhen Jin, Zhongsheng Yu, Tao Cai, Renji...
Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states
医学研究进展 | | 2018-03-01 10:29
Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states
Xiaoyuan Zhou, Minghui Li, Deyuan Su, Qi Jia, Huan Li, Xueming Li & Jian Yang
Nature Structural & Molecular Biology volume 24, pages 1146–1154 ...
α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
医学研究进展 | | 2016-05-10 17:13
α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
Mengping Weia,1, Jian Zhanga,1, Moye Jiaa,1, Chaojuan Yanga,1, Yunlong Pana, Shuaiqi Lia, Yiwen Luoa, Junyuan Z...
The type I interferon-IRF7 axis mediates transcriptional expression f Usp25
医学研究进展 | | 2016-05-10 17:08
The type I interferon-IRF7 axis mediates transcriptional expression f Usp25
Yujie Ren1, Yin Zhao1, Dandan Lin1, Ximing Xu1, Qiyun Zhu2, Jing Yao1, Hong-Bing Shu1 and Bo Zhong1*
Author Affiliations
1 Wuhan University, China;
2 Lanzhou Vete...
High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China
医学研究进展 | | 2016-05-10 17:05
High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China
ABSTRACT
In China, and most other countries, the first-line empirical mono-antimicrobial therapy against gonorrhoea consists of extended-...
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